![]() ![]() The cannabis Sativa plant is a member of the Cannabaceae family, which includes several other plants such as hops and hackberry. The research into cannabis's chemical compounds are primarily focused on THC and CBD, but early animal and human trials suggest that CBGa may effectively target unique pathways that may support viral infection, heart health, and metabolic disorders.ĬBGa products are limited, but as more research and new cannabis plant extraction methods professes, we can expect to see more CBGa-focused products hit the market. This slight variation in molecule structure may have unique effects in terms of pharmacology. The Cannabis plant contains over 100 different active compounds, including cannabigerolic acid (CBGa).ĬBGa is known as the "mother cannabinoid" because it eventually transforms into CBDa, THC, and CBCa as the cannabis plant matures.Įxposure to heat or UV breaks off the carboxylic acid chain, represented with the letter "a" leaving behind CBG. So, what does this all mean, and are there any health benefits to be had from CBGa and other raw cannabis plant cannabinoids? While CBD or cannabidiol is the main active compound found in hemp plants, it's not the only cannabinoid worth looking at.Īs researchers dive deeper into hemp compounds, we find a wealth of potential wellness secrets to unlock.Ĭannabigerolic acid, or CBGa, is a minor cannabinoid found naturally in young, flowering cannabis plants-and it's nicknamed the "mother cannabinoid" as it's the precursor to the two main cannabinoids, CBDa (cannabidiolic acid) and THCa (tetrahydrocannabinolic acid) that eventually turn into CBD and THC through a process called decarboxylation.ĬBGa and any other cannabinoid with the "a" affixed to it is the natural form of the compound that still contains a carboxylic acid group to the molecule. Explicit inclusion of sickle cell disease as a qualifying condition for medical marijuana might reduce illicit marijuana use and related risks and costs to both persons living with sickle cell disease and society.Ĭannabinoid marijuana medical marijuana sickle cell disease.It seems like someone is touting the benefits of CBD oil everywhere you look. Conclusion: Our findings and those of others create a rationale for research into the possible therapeutic effects of marijuana or cannabinoids, the presumed active constituents of marijuana, in sickle cell disease. In the interval ∼1.5 years, 44 patients have requested certification. Subsequent to these studies, sickle cell disease became a qualifying condition for medical marijuana in our state. Among 57 patients who had at least one urine drug test, 18% tested positive for cannabinoids only, 12% tested positive for cocaine and/or phencyclidine only, and 5% tested positive for both cannabinoids and cocaine/phencyclidine. Among users, most endorsed five medicinal indications a minority reported recreational use. Results: Among 58 patients surveyed, 42% reported marijuana use within the past 2 years. We tracked patient requests for certification for medical marijuana. We reviewed institutional records for clinically driven urine drug testing. We surveyed our patients with a brief, anonymous, paper-and-pen instrument. Materials and Methods: We practice at an urban, academic medical center and provide primary, secondary, and tertiary care for ∼130 adults living with sickle cell disease. We were aware that some of our patients living with sickle cell disease used illicit marijuana, and we sought more information about this. ![]() Introduction: Legal access to marijuana, most frequently as "medical marijuana," is becoming more common in the United States, but most states do not specify sickle cell disease as a qualifying condition. ![]()
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